Bioactive Compounds from Marine Bacteria and Fungi

نویسندگان

  • Abdessamad Debbab
  • Amal H. Aly
  • Wen H. Lin
  • Peter Proksch
چکیده

Marine bacteria and fungi are of considerable importance as new promising sources of a huge number of biologically active products. Some of these marine species live in a stressful habitat, under cold, lightless and high pressure conditions. Surprisingly, a large number of species with high diversity survive under such conditions and produce fascinating and structurally complex natural products. Up till now, only a small number of microorganisms have been investigated for bioactive metabolites, yet a huge number of active substances with some of them featuring unique structural skeletons have been isolated. This review covers new biologically active natural products published recently (2007-09) and highlights the chemical potential of marine microorganisms, with focus on bioactive products as well as on their mechanisms of action.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Review Paper-marine Microbial Bioactive Compounds

Oceans have borne most of the biological activities on our planet. A number of biologically active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti-microtubule, anti-proliferative, cytotoxic, photo protective, as well as antibiotic and antifouling properties, have been isolated to date from marine sources. The marine environment also represents a largely unexplore...

متن کامل

Bioactivity potential of some marine algae from south of Iran

Algae are composed of a diverse group of various aquatic organisms. Secondary or primary metabolites from these organisms may be potential bioactive compounds of interest for use in the development of new pharmaceutical agents. In this research, four species of marine algae, Ulva lactuca, Padina pavonica, Colpomenia sinuosa and Cystoseira myrica, isolated from Persian Gulf coasts were evaluated...

متن کامل

Isolation of Halophilic Bacteria from Maharlu salt Lake - Iran and their evaluation for the production of bioactive compounds

Halophilic bacteria grow over a wide range of salt concentrations. In this study we aimed to isolate and screen out the halophilic bacteria and to determine their activity for production of the bioactive compounds. A total of 50 water, sediments and soil samples were collected from Maharlu salt lake in southern region of Fars-Iran and subjected for isolation of the bioactive compound producing ...

متن کامل

Deep Subseafloor Fungi as an Untapped Reservoir of Amphipathic Antimicrobial Compounds

The evolving global threat of antimicrobial resistance requires a deep renewal of the antibiotic arsenal including the isolation and characterization of new drugs. Underexplored marine ecosystems may represent an untapped reservoir of novel bioactive molecules. Deep-sea fungi isolated from a record-depth sediment core of almost 2000 m below the seafloor were investigated for antimicrobial activ...

متن کامل

A study on biological activity of marine fungi from different habitats in coastal regions

In recent years, marine fungi have become an important source of active marine natural products. Former researches are limited in habitats selection of fungi with bioactive compounds. In this paper were to measure antibacterial and antitumor cell activity for secondary metabolites of marine fungi, which were isolated from different habitats in coastal regions. 195 strains of marine fungi were i...

متن کامل

Marine Compounds and their Antimicrobial Activities

Natural products have been regarded as important sources that could produce potential chemotherapeutic agents. In the search for new bioactive entities, investigations were expanded to marine habitats. Mankind has known for the last several thousand years that marine organisms contain substances capable of potent biological activity. However, the first serious investigation of marine organisms ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2010